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In kidney tubular epithelial cells, activation of EPAC-RAP1 signaling was shown to reduce the ROS production by preventing mitochondrial superoxide formation [9]
Neo May 11, 2024, 4:09am #1 IMG_728811791181 187 KB Functional and multi-omic aging rejuvenation with GLP-1R agonism Importantly, the beneficial effects are specific to aged mice, not young adults, and are achieved with a low dosage of GLP-1RA which has a negligible impact on food consumption and body weight
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